Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648512 | 1.00 | MEN1 (0.43) | MEN1KMT2AMITFMAPTHTT | |
| SCHEMBL21648507 | 0.89 | MEN1 (0.55) | MEN1KMT2AHTTTRPM8CYP19A1 | |
| SCHEMBL21648508 | 0.89 | MEN1 (0.55) | MEN1KMT2AHTTTRPM8CYP19A1 | |
| SCHEMBL21648509 | 0.89 | MEN1 (0.55) | MEN1KMT2AHTTTRPM8CYP19A1 | |
| SCHEMBL23515571 | 0.81 | MEN1 (0.40) | MEN1KMT2AMITFMAPTHTT | |
| SCHEMBL23515570 | 0.77 | MEN1 (0.42) | MEN1KMT2ATRPM8CYP19A1PDE5A | |
| SCHEMBL21648504 | 0.72 | MAPKAPK2 (0.46) | MAPTSIRT1 | |
| SCHEMBL21648506 | 0.72 | MAPKAPK2 (0.46) | MAPTSIRT1 | |
| SCHEMBL21648544 | 0.71 | MEN1 (0.58) | MEN1KMT2AHTTTRPM8CYP19A1 | |
| SCHEMBL21648531 | 0.71 | MEN1 (0.58) | MEN1KMT2AHTTTRPM8CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020021489-A2 | DISCOVERY OF NOVEL FIRST IN CLASS NATURE-INSPIRED COMPOUNDS TARGETING THE MITOCHONDRIAL FUNCTION AND PHARMACEUTICAL COMPOSITION THEREOF | UNIVERSITY OF SHARJAH (AE) | 2020-01-30 | — | — | WO | disclosed |