Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.42 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648529 | 1.00 | MEN1 (0.53) | MEN1KMT2ATRPM8NPC1RAB9A | |
| SCHEMBL21648517 | 1.00 | MEN1 (0.53) | MEN1KMT2ATRPM8NPC1RAB9A | |
| SCHEMBL23515571 | 0.83 | MEN1 (0.40) | MEN1KMT2ATRPM8NPC1RAB9A | |
| SCHEMBL21648507 | 0.81 | MEN1 (0.55) | MEN1KMT2ATRPM8NPC1RAB9A | |
| SCHEMBL21648508 | 0.81 | MEN1 (0.55) | MEN1KMT2ATRPM8NPC1RAB9A | |
| SCHEMBL21648509 | 0.81 | MEN1 (0.55) | MEN1KMT2ATRPM8NPC1RAB9A | |
| SCHEMBL21648518 | 0.78 | CHRNA7 (0.42) | MEN1KMT2ATSHRHTTPDE5A | |
| SCHEMBL21648536 | 0.78 | CHRNA7 (0.42) | MEN1KMT2ATSHRHTTPDE5A | |
| SCHEMBL21648535 | 0.78 | CHRNA7 (0.42) | MEN1KMT2ATSHRHTTPDE5A | |
| SCHEMBL21648544 | 0.71 | MEN1 (0.58) | MEN1KMT2ATRPM8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020021489-A2 | DISCOVERY OF NOVEL FIRST IN CLASS NATURE-INSPIRED COMPOUNDS TARGETING THE MITOCHONDRIAL FUNCTION AND PHARMACEUTICAL COMPOSITION THEREOF | UNIVERSITY OF SHARJAH (AE) | 2020-01-30 | — | — | WO | disclosed |