Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25043140 | 0.84 | BRD4 (0.49) | BRD4 | |
| SCHEMBL20094747 | 0.84 | BRD4 (0.56) | BRD4 | |
| SCHEMBL19930841 | 0.84 | BRD4 (0.51) | BRD4 | |
| SCHEMBL19931123 | 0.84 | BRD4 (0.52) | BRD4 | |
| Trotabresib SCHEMBL16650974 | 0.84 | BRD4 (0.74) | BRD4 | |
| Trotabresib SCHEMBL29380951 | 0.84 | BRD4 (0.74) | BRD4 | |
| SCHEMBL29848673 | 0.83 | BRD4 (0.74) | BRD4 | |
| SCHEMBL16650684 | 0.83 | BRD4 (0.74) | BRD4 | |
| SCHEMBL25043104 | 0.83 | BRD4 (0.52) | BRD4 | |
| SCHEMBL19930814 | 0.82 | BRD4 (0.56) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023438-A2 | PROCESS FOR THE PREPARATION OF BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2020-01-30 | — | — | WO | disclosed |