Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557514 | 0.77 | TSHR (0.50) | PIK3CDTSHRCHRM2CHRM5CHRM1 | |
| Dimethyl Sulfone SCHEMBL28250956 | 0.77 | PIK3CD (0.52) | PIK3CDTSHRCHRM2CHRM5CHRM1 | |
| SCHEMBL27958225 | 0.75 | PIK3CD (0.59) | PIK3CDTSHRCHRM2CHRM5CHRM1 | |
| SCHEMBL18635 | 0.75 | — | — | |
| SCHEMBL4278259 | 0.74 | KMT2A (0.59) | PIK3CDTSHRCHRM2CHRM5CHRM1 | |
| SCHEMBL261644 | 0.74 | PIK3CD (0.58) | PIK3CDTSHRCHRM2CHRM5CHRM1 | |
| SCHEMBL4942902 | 0.74 | PIK3CD (0.48) | PIK3CDTSHRCHRM2CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL23248746 | 0.73 | — | — | |
| Water SCHEMBL6122410 | 0.73 | — | — | |
| Water SCHEMBL6122968 | 0.73 | PIK3CD (0.57) | PIK3CDTSHRCHRM2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020020377-A1 | FUSED RING DERIVATIVE USED AS FGFR4 INHIBITOR | 北京加科思新药研发有限公司 | 2020-01-30 | — | — | WO | disclosed |