Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15188860 | 0.79 | BACE1 (0.43) | BACE1APP | |
| SCHEMBL21654309 | 0.78 | BACE1 (0.42) | BACE1APP | |
| SCHEMBL20467074 | 0.78 | BACE1 (0.42) | BACE1APP | |
| SCHEMBL21654296 | 0.77 | BACE1 (0.44) | BACE1APP | |
| SCHEMBL14727560 | 0.76 | BACE1 (0.48) | BACE1APP | |
| SCHEMBL9948747 | 0.76 | BACE1 (0.44) | BACE1APP | |
| SCHEMBL14845678 | 0.76 | BACE1 (0.44) | BACE1APP | |
| SCHEMBL15168930 | 0.76 | BACE1 (0.44) | BACE1APP | |
| SCHEMBL9948749 | 0.76 | BACE1 (0.44) | BACE1APP | |
| SCHEMBL10249928 | 0.76 | BACE1 (0.44) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176172-B1 | SPIROIMIDAZOLE COMPOUNDS AND THEIR USE AS BACE INHIBITORS | ASTRAZENECA AB (SE) | 2020-01-29 | — | — | EP | disclosed |