⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21099399 | 0.80 | — | — | |
| SCHEMBL11823349 | 0.76 | — | — | |
| SCHEMBL9130456 | 0.75 | — | — | |
| SCHEMBL30493454 | 0.75 | — | — | |
| SCHEMBL9252734 | 0.75 | — | — | |
| SCHEMBL4137228 | 0.75 | — | — | |
| SCHEMBL18914210 | 0.73 | — | — | |
| SCHEMBL13726021 | 0.73 | — | — | |
| SCHEMBL13114690 | 0.73 | CCR1 (0.35) | — | |
| SCHEMBL10167888 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020534-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-02-23 | — | — | WO | disclosed |
| US-10544133-B2 | Heteroaryl substituted pyridyl compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-01-28 | — | — | US | disclosed |