Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657808 | 0.88 | PTPRC (0.55) | PTPRCPTPN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL16921221 | 0.86 | CYP2C19 (0.48) | ELANEALDH1A1MAPTNPSR1EGFR | |
| SCHEMBL21657837 | 0.85 | PTPRC (0.55) | PTPRCPTPN1ALDH1A1MAPTNPSR1 | |
| SCHEMBL16921214 | 0.84 | ELANE (0.49) | ELANESLC37A4ALDH1A1MAPTNPSR1 | |
| SCHEMBL21657777 | 0.82 | KMT2A (0.53) | ELANEALDH1A1MAPTEGFRPIM1 | |
| SCHEMBL15427193 | 0.82 | EGFR (0.48) | ELANEALDH1A1MAPTNPSR1EGFR | |
| SCHEMBL15427181 | 0.82 | EGFR (0.48) | ELANEALDH1A1MAPTNPSR1EGFR | |
| SCHEMBL15427180 | 0.82 | EGFR (0.48) | ELANEALDH1A1MAPTNPSR1EGFR | |
| SCHEMBL16921219 | 0.80 | EGFR (0.46) | PTPRCELANEEGFRPIM1MEN1 | |
| SCHEMBL16921213 | 0.79 | CYP1A2 (0.56) | ELANEALDH1A1MAPTNPSR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872474-B1 | ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2022-01-19 | — | — | EP | disclosed |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | PTPRC 4387/4885PTPN1 3445/4885ELANE 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.