Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.41 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21660630 | 0.90 | KDM4E (0.46) | KDM4EESR1ESR2ATML3MBTL1 | |
| SCHEMBL21660657 | 0.89 | RECQL (0.51) | KDM4EESR1ESR2ATML3MBTL1 | |
| SCHEMBL21660560 | 0.87 | ESR1 (0.44) | KDM4EESR1ESR2L3MBTL1KMT2A | |
| SCHEMBL21660629 | 0.87 | PTGER4 (0.43) | KDM4EESR1ESR2ATML3MBTL1 | |
| SCHEMBL21660627 | 0.84 | KDM4E (0.43) | KDM4EESR1ESR2KMT2AMEN1 | |
| SCHEMBL21660473 | 0.84 | KMT2A (0.46) | KDM4EESR1ESR2L3MBTL1KMT2A | |
| SCHEMBL21660757 | 0.84 | MAPT (0.41) | KDM4EESR1ESR2ATML3MBTL1 | |
| SCHEMBL21660681 | 0.81 | PTGER4 (0.39) | KDM4EESR1ESR2ATML3MBTL1 | |
| SCHEMBL10055038 | 0.80 | ESR1 (0.64) | KDM4EESR1ESR2ATML3MBTL1 | |
| SCHEMBL12205094 | 0.80 | ESR1 (0.64) | KDM4EESR1ESR2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583104-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-06-09 | — | — | EP | disclosed |
| US-10923665-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-02-16 | — | — | US | disclosed |
| US-20200044162-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10923665-B2 | Materials for organic electroluminescent devices | OR10J3, L1CAM, EPCAM | KDM4E 1917/4885ESR1 78/4885ESR2 244/4885 |
| US-20200044162-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, L1CAM, EPCAM | KDM4E 1917/4885ESR1 78/4885ESR2 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.