SCHEMBL21660686

SCHEMBL21660686

c1ccc2c(c1)ccc1ccc(-n3cc4c5ccccc5nc-4c4ccccc43)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
TERT O14746 1/20 0.38
PRKCG P05129 5/20 0.37
PRKCB P05771 5/20 0.37
PRKCA P17252 5/20 0.37
GSK3B P49841 5/20 0.37
KCNH2 Q12809 5/20 0.37
PRKCZ Q05513 2/20 0.37
PRKCD Q05655 2/20 0.37
PDE4B Q07343 2/20 0.36
PDE4D Q08499 2/20 0.36
PDE4A P27815 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HIF1A Q16665 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21660634 0.89 KDM4E (0.43) KDM4EPOLBCTDSP1TERTPRKCG
SCHEMBL21660484 0.84 KDM4E (0.55) KDM4EPOLBCTDSP1TERTPRKCG
SCHEMBL21660564 0.83 KDM4E (0.45) KDM4EPOLBCTDSP1TERTPDE4B
SCHEMBL21660705 0.81 KDM4E (0.44) KDM4EPOLBCTDSP1PDE4BPDE4D
SCHEMBL21660737 0.81 KDM4E (0.47) KDM4EPOLBCTDSP1PDE4BPDE4D
SCHEMBL21660569 0.80 MEN1 (0.44) KDM4EPOLBCTDSP1PDE4BPDE4D
SCHEMBL21660561 0.80 KDM4E (0.42) KDM4EPOLBCTDSP1TERTPDE4B
SCHEMBL21660563 0.79 POLB (0.37) KDM4EPOLBCTDSP1TERTPRKCG
SCHEMBL21660712 0.78 KDM4E (0.44) KDM4EPOLBCTDSP1PDE4BPDE4D
SCHEMBL21660696 0.74 KDM4E (0.42) KDM4EPOLBCTDSP1TERTPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3583104-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-06-09 EP disclosed
US-10923665-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-02-16 US disclosed
US-20200044162-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10923665-B2 Materials for organic electroluminescent devices OR10J3, L1CAM, EPCAM KDM4E 1917/4885POLB 1900/4885CTDSP1 4722/4885
US-20200044162-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, L1CAM, EPCAM KDM4E 1917/4885POLB 1900/4885CTDSP1 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.