Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25082565 | 1.00 | MEN1 (0.48) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL16126138 | 0.89 | MEN1 (0.46) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL16126120 | 0.89 | MEN1 (0.46) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL16126132 | 0.89 | MEN1 (0.46) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL14602768 | 0.88 | USP2 (0.61) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL19199175 | 0.88 | USP2 (0.61) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL26668826 | 0.86 | MEN1 (0.48) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL13499227 | 0.84 | USP2 (0.50) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL20875802 | 0.84 | USP2 (0.50) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL11522655 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025517-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | WO | disclosed |