Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21645085 | 1.00 | USP2 (0.41) | USP2SMN1; SMN2HDAC2CYP11B2USP30 | |
| SCHEMBL13993955 | 1.00 | USP2 (0.41) | USP2SMN1; SMN2HDAC2CYP11B2USP30 | |
| SCHEMBL12180144 | 0.91 | HPGD (0.40) | USP2SMN1; SMN2HDAC2USP30NR1H2 | |
| SCHEMBL14242637 | 0.91 | HPGD (0.40) | USP2SMN1; SMN2HDAC2USP30NR1H2 | |
| SCHEMBL343979 | 0.91 | USP2 (0.47) | USP2SMN1; SMN2HDAC2NR1H2HDAC1 | |
| SCHEMBL13779824 | 0.87 | USP2 (0.42) | USP2SMN1; SMN2NR1H2HPGDEPHX2 | |
| SCHEMBL16797307 | 0.86 | USP2 (0.42) | USP2SMN1; SMN2HDAC2CYP11B2USP30 | |
| SCHEMBL21216177 | 0.86 | USP2 (0.42) | USP2SMN1; SMN2HDAC2CYP11B2USP30 | |
| SCHEMBL19459465 | 0.86 | USP2 (0.42) | USP2SMN1; SMN2HDAC2CYP11B2USP30 | |
| SCHEMBL28864062 | 0.86 | USP2 (0.42) | USP2SMN1; SMN2HDAC2CYP11B2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513024-A | TLR7/8 antagonists and uses thereof | 默克专利股份公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020025517-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | WO | disclosed |