Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22519410 | 0.82 | CYP1A2 (0.37) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL23866631 | 0.82 | CYP1A2 (0.37) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL14221999 | 0.81 | KMT2A (0.32) | KMT2AALDH1A1 | |
| SCHEMBL1515612 | 0.78 | — | — | |
| SCHEMBL4121086 | 0.78 | CYP3A4 (0.37) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL22481368 | 0.76 | KDM4E (0.35) | KDM4EKMT2A | |
| SCHEMBL19575870 | 0.76 | CYP1A2 (0.38) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL4291393 | 0.76 | CYP1A2 (0.38) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL18934852 | 0.76 | KDM4E (0.48) | KDM4EKMT2A | |
| SCHEMBL4133242 | 0.76 | CYP3A4 (0.40) | KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025517-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | WO | disclosed |