Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20905642 | 0.83 | — | — | |
| SCHEMBL10641279 | 0.78 | MAPK1 (0.32) | KMT2A | |
| SCHEMBL20718023 | 0.77 | KDM1A (0.44) | KDM1A | |
| SCHEMBL15739795 | 0.77 | KDM1A (0.44) | KDM1A | |
| SCHEMBL24268261 | 0.76 | — | — | |
| SCHEMBL19182919 | 0.73 | KDM1A (0.42) | KDM1AKCNH2 | |
| SCHEMBL12225222 | 0.72 | KDM1A (0.41) | KDM1A | |
| SCHEMBL16110021 | 0.72 | KDM1A (0.36) | KDM1A | |
| SCHEMBL13605225 | 0.71 | KDM1A (0.38) | KDM1A | |
| SCHEMBL22519389 | 0.71 | KCNH2 (0.40) | KDM1AKMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025517-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | WO | disclosed |