Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24404814 | 0.84 | TLR8 (0.52) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL16633643 | 0.84 | TLR8 (0.52) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL19829021 | 0.84 | TLR8 (0.52) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21645234 | 0.84 | ELANE (0.38) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21661048 | 0.83 | TSHR (0.38) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21645078 | 0.83 | TSHR (0.38) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21645087 | 0.82 | TDP1 (0.37) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21645148 | 0.82 | TLR8 (0.37) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21660981 | 0.81 | TLR8 (0.39) | ALDH1A1GAASMN1; SMN2TLR8TDP1 | |
| SCHEMBL21661197 | 0.78 | TLR8 (0.39) | ALDH1A1GAASMN1; SMN2TLR8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025517-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | WO | disclosed |