Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 19/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20679562 | 0.89 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL30675629 | 0.89 | ENPP1 (1.00) | ENPP1 | |
| SCHEMBL21663585 | 0.83 | ENPP1 (0.79) | ENPP1ALDH1A1MAPTHPGD | |
| SCHEMBL21663412 | 0.78 | ENPP1 (0.80) | ENPP1 | |
| SCHEMBL21663424 | 0.78 | ENPP1 (0.80) | ENPP1 | |
| SCHEMBL21663582 | 0.76 | ENPP1 (0.79) | ENPP1MAPT | |
| SCHEMBL20679588 | 0.72 | ENPP1 (1.00) | ENPP1ALDH1A1MAPT | |
| SCHEMBL30675573 | 0.72 | ENPP1 (1.00) | ENPP1ALDH1A1MAPT | |
| SCHEMBL15288025 | 0.72 | MAPT (0.71) | ENPP1ALDH1A1MAPTHPGD | |
| SCHEMBL20687574 | 0.71 | ENPP1 (1.00) | ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028724-A1 | SUBSTITUTED-3H-IMIDAZO[4,5-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE SERIES OF NOVEL ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE-1 (ENPP1) AND STIMULATOR FOR INTERFERON GENES (STING) MODULATORS AS CANCER IMMUNOTHERAPEUTICS | Stingray Therapeutics, Inc. (US) | 2020-02-06 | — | — | WO | disclosed |