⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21907046 | 0.96 | — | — | |
| SCHEMBL20128804 | 0.82 | — | — | |
| SCHEMBL20329980 | 0.81 | — | — | |
| SCHEMBL20231174 | 0.76 | — | — | |
| SCHEMBL20232145 | 0.75 | — | — | |
| SCHEMBL20233533 | 0.73 | — | — | |
| SCHEMBL20128815 | 0.70 | ATM (0.32) | — | |
| SCHEMBL20133323 | 0.69 | — | — | |
| SCHEMBL20133433 | 0.69 | ATM (0.33) | — | |
| SCHEMBL21933644 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038513-A1 | MODULATORS OF FAK PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
| US-20200038378-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | GENENTECH, INC. | 2020-02-06 | — | — | US | disclosed |