Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166675 | 0.80 | HRH4 (0.69) | HRH4HTR3A | |
| SCHEMBL27738435 | 0.78 | HRH4 (0.71) | HRH4HTR3A | |
| SCHEMBL2168071 | 0.78 | HRH4 (0.59) | HRH4HTR3A | |
| SCHEMBL2169029 | 0.77 | HRH4 (0.69) | HRH4HTR3A | |
| SCHEMBL2167178 | 0.77 | HRH4 (0.64) | HRH4HTR3A | |
| SCHEMBL2166821 | 0.77 | HRH4 (0.82) | HRH4HTR3A | |
| SCHEMBL1616232 | 0.77 | HRH4 (0.72) | HRH4 | |
| SCHEMBL2165190 | 0.76 | HRH4 (0.80) | HRH4HTR3A | |
| SCHEMBL2167266 | 0.76 | HRH4 (0.89) | HRH4 | |
| SCHEMBL607510 | 0.75 | HRH4 (0.66) | HRH4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985745-B2 | Including inflammatory pain, post surgical pain, and neuropathic pain; administering a histamine H4 receptor ligand alone or in combination with a histamine H1, H2, or H3 receptor antagonist or an enzyme inhibitor | ABBOTT LABORATORIES (US) | 2011-07-26 | — | — | US | disclosed |
| US-20080194538-A1 | Method for Pain Treatment | ABBVIE INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194538-A1 | Method for Pain Treatment | HRH4, HRH3, HRH2 | HRH4 1/4885HTR3A 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.