SCHEMBL2166510

SCHEMBL2166510

CC(=CCc1ccc2c(O)c(C)c(C)c(O)c2c1)CCCC(C)CCCC(C)CCCC(C)C

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.49
PDE4A P27815 1/20 0.49
SNCA P37840 1/20 0.49
PDE3A Q14432 1/20 0.49
PTPN1 P18031 3/20 0.47
TRPV1 Q8NER1 1/20 0.41
PSEN1 P49768 3/20 0.39
PTPN2 P17706 1/20 0.36
CDC25B P30305 1/20 0.36
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1257001 0.88 PTGS1 (0.47) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL9360006 0.82 PTGS1 (0.52) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL9360002 0.82 PTGS1 (0.52) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL9356606 0.82 PTPN1 (0.52) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL9356601 0.82 PTPN1 (0.52) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL869358 0.81 PTGS1 (0.57) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL29357300 0.81 PTGS1 (0.57) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL28023376 0.81 PTGS1 (0.57) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL29474878 0.81 PTGS1 (0.57) PTGS1PDE4ASNCAPDE3APTPN1
SCHEMBL17299611 0.81 PTPN1 (0.46) PTGS1PDE4ASNCAPDE3APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110185456-A1 Annotatd plant genes CHEIKH NORDINE 2011-07-28 US disclosed
US-20100100987-A1 NUCLEIC ACID MOLECULES AND OTHER MOLECULES ASSOCIATED WITH THE TOCOPHEROL PATHWAY BHAT BARKUR G 2010-04-22 US disclosed
US-7655777-B2 Nucleic acid molecules associated with the tocopherol pathway MONSANTO TECHNOLOGY LLC (US) 2010-02-02 US disclosed
US-20080034453-A1 Nucleotide sequences coding maize and/or soybean proteinfor use in genome mapping, identification and analysis; plant breeding MONSANTO TECHNOLOGY LLC 2008-02-07 US disclosed
US-20070143878-A1 Nucleic acid molecules and other molecules associated with the tocopherol pathway MONSANTO TECHNOLOGY LLC 2007-06-21 US disclosed