Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617183 | 0.74 | SMN1; SMN2 (0.38) | CYP4F2CYP4A11TDP1SMN1; SMN2LMNA | |
| SCHEMBL19696594 | 0.68 | TDP1 (0.35) | CYP4F2CYP4A11TDP1SMN1; SMN2LMNA | |
| SCHEMBL7808732 | 0.67 | — | — | |
| 1,4-Butanediol SCHEMBL409238 | 0.66 | — | — | |
| SCHEMBL3952086 | 0.66 | — | — | |
| SCHEMBL25319811 | 0.65 | CYP4F2 (0.41) | CYP4F2CYP4A11TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6843199 | 0.65 | CYP4F2 (0.41) | CYP4F2CYP4A11TDP1SMN1; SMN2LMNA | |
| SCHEMBL454593 | 0.64 | — | — | |
| SCHEMBL14978154 | 0.64 | SMN1; SMN2 (0.44) | CYP4F2CYP4A11TDP1SMN1; SMN2LMNA | |
| SCHEMBL30893155 | 0.64 | SMN1; SMN2 (0.38) | CYP4F2CYP4A11TDP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053600-B1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC (US) | 2020-01-29 | — | — | EP | disclosed |