Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539354 | 0.84 | PI4KB (0.53) | LCKPI4KBCA1CA2 | |
| SCHEMBL27459070 | 0.83 | PI4KB (0.42) | LCKPI4KBCA1CA2 | |
| SCHEMBL3509100 | 0.80 | LCK (0.46) | LCKPI4KBCA1CA2 | |
| SCHEMBL20421990 | 0.77 | CA1 (0.44) | LCKPI4KBCA1CA2 | |
| SCHEMBL2174374 | 0.75 | LCK (0.52) | LCKPI4KBCA1CA2 | |
| SCHEMBL9225190 | 0.75 | LCK (0.49) | LCKPI4KBCA1CA2 | |
| SCHEMBL1796679 | 0.75 | LCK (0.54) | LCKPI4KBCA1CA2 | |
| SCHEMBL539642 | 0.74 | LCK (0.52) | LCKPI4KBCA1CA2 | |
| SCHEMBL7496332 | 0.74 | LCK (0.48) | LCKPI4KBCA1CA2 | |
| SCHEMBL3510497 | 0.73 | LCK (0.43) | LCKPI4KBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028115-A1 | 5-METHYL-4-FLUORO-THIAZOL-2-YL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2020-02-06 | — | — | WO | disclosed |