SCHEMBL21666

SCHEMBL21666

FC(F)S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20610199 0.93
SCHEMBL28562959 0.83
SCHEMBL1030871 0.72
SCHEMBL24099 0.72
SCHEMBL17991 0.72
SCHEMBL20977428 0.72
SCHEMBL15426786 0.72
SCHEMBL149079 0.72
SCHEMBL1032163 0.72
SCHEMBL21875166 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7890 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4143184-B1 COMPOUNDS USEFUL FOR INHIBITING RET KINASE LILLY CO ELI (US) 2025-04-23 EP claimed
EP-4392419-A1 NOVEL PYRAZINYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2024-07-03 EP claimed
EP-4146643-B1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2024-05-29 EP claimed
CN-118103364-A Pyrazinyl-triazole compounds as pesticides 拜耳公司 2024-05-28 CN claimed
US-11970485-B2 RET kinase inhibitors ELI LILLY AND COMPANY (US) 2024-04-30 US claimed
CN-117836295-A Substituted 1, 4-dihydro-1, 6-naphthyridine amides and use thereof 上海拓界生物医药科技有限公司 2024-04-05 CN claimed
EP-4041721-B1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2024-03-06 EP claimed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN claimed
US-11851408-B2 Method for preparing pyridine compound substituted with trifluoromethylthio, difluoromethylthio or trifluoromethyl in meta position NANKAI UNIVERSITY (CN) 2023-12-26 US claimed
CN-117263950-A Pyridazine compound, pharmaceutical composition and application thereof 上海优理惠生医药有限公司 2023-12-22 CN claimed
EP-0039168-A1 Amidoximether insecticides RHONE-POULENC INC. (US) 1981-11-04 EP claimed
US-4268525-A Amidoximether insecticides MOBIL OIL CORPORATION (US) 1981-05-19 US claimed
EP-0024888-A2 Ketoximinoether insecticides RHONE-POULENC INC. (US) 1981-03-11 EP claimed
US-4207241-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTIPRURITIC AGENTS SYNTEX CORPORATION (US) 1980-06-10 US claimed
US-4010179-A ANTIMICROBIAL, ANTINEOPLASTIC AMERICAN CYANAMID COMPANY (US) 1977-03-01 US claimed
US-3998966-A Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof SYNTEX CORPORATION (PM) 1976-12-21 US claimed
US-3978116-A ANALGESIC, ANTIPYRETIC SYNTEX CORPORATION (PM) 1976-08-31 US claimed
US-3960936-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS SYNTEX CORPORATION (PM) 1976-06-01 US claimed
US-3958012-A ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIVITY SYNTEX CORPORATION (US) 1976-05-18 US claimed
US-3935273-A ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC SYNTEX CORPORATION (US) 1976-01-27 US claimed