Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | MTOR | P42345 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MLNR | O43193 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942616 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL21666077 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL813024 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL5902706 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL5902702 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL5903230 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL5902708 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL5903224 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL20340495 | 0.81 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| Desmethylsertraline SCHEMBL4781834 | 0.81 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020025646-A1 | AN OMEGA-TRANSAMINASE ENZYME | UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) | 2020-02-06 | — | — | WO | disclosed |
| EP-3604507-A1 | AN OMEGA-TRANSAMINASE ENZYME | University College Cork-National University of Ireland, Cork (IE) | 2020-02-05 | — | — | EP | disclosed |