Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 9/20 | 0.62 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.62 |
| ▸ | ACHE | P22303 | 10/20 | 0.53 |
| ▸ | BACE1 | P56817 | 10/20 | 0.53 |
| ▸ | BCHE | P06276 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271477 | 0.89 | VEGFA (0.76) | VEGFAEGLN1ACHEBACE1BCHE | |
| SCHEMBL272882 | 0.83 | VEGFA (0.70) | VEGFAEGLN1ACHEBACE1BCHE | |
| SCHEMBL19478697 | 0.80 | EGLN1 (0.78) | VEGFAEGLN1ACHEBACE1BCHE | |
| SCHEMBL278141 | 0.78 | EGLN1 (0.79) | VEGFAEGLN1ACHEBACE1BCHE | |
| SCHEMBL272935 | 0.77 | EGLN1 (1.00) | VEGFAEGLN1ACHEBACE1BCHE | |
| SCHEMBL12649394 | 0.76 | VEGFA (0.70) | VEGFAEGLN1ACHEBCHE | |
| SCHEMBL16789163 | 0.76 | EGLN1 (0.78) | VEGFAEGLN1ACHEBACE1BCHE | |
| SCHEMBL278202 | 0.74 | VEGFA (1.00) | VEGFAEGLN1KMT2APOLB | |
| SCHEMBL278211 | 0.72 | VEGFA (0.75) | VEGFAEGLN1MEN1KMT2A | |
| SCHEMBL12598832 | 0.71 | VEGFA (0.73) | VEGFAEGLN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3603644-A1 | PROLYL HYDROXYLASE INHIBITORS | Aerpio Therapeutics, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |