SCHEMBL21669604

SCHEMBL21669604

C=CCCC(=S)c1ccon1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21669602 0.79 CHRNA4 (0.36) CHRNA4
SCHEMBL21645685 0.72 DAGLA (0.43)
SCHEMBL10402674 0.69
SCHEMBL30075112 0.66
SCHEMBL4604627 0.65
SCHEMBL7591365 0.64 POLB (0.40)
SCHEMBL6808143 0.62 HDAC3 (0.38) CHRNA4
SCHEMBL11166684 0.61
SCHEMBL16969303 0.60
SCHEMBL1396502 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020028150-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME CORP. (US) 2020-02-06 WO disclosed