Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670348 | 1.00 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2GLATP53 | |
| SCHEMBL21670498 | 0.89 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL21670303 | 0.88 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL21669858 | 0.88 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL21669788 | 0.88 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2TP53GAA | |
| SCHEMBL21670251 | 0.88 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL21670349 | 0.88 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2TP53GAA | |
| SCHEMBL21669809 | 0.87 | GAA (0.68) | MEN1KMT2ASMN1; SMN2GLAGAA | |
| SCHEMBL21670316 | 0.87 | GAA (0.68) | MEN1KMT2ASMN1; SMN2GLAGAA | |
| SCHEMBL21669776 | 0.87 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028482-A1 | SMALL MOLECULES THAT SENSITIZE HIV-1 INFECTED CELLS TO ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-02-06 | — | — | WO | disclosed |