Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 1.00 |
| ▸ | KLK1 | P06870 | 4/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485692 | 1.00 | KLKB1 (1.00) | KLKB1KLK1 | |
| SCHEMBL21669879 | 0.93 | KLKB1 (0.87) | KLKB1KLK1 | |
| SCHEMBL14555002 | 0.93 | KLKB1 (0.87) | KLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL15901158 | 0.92 | KLKB1 (0.86) | KLKB1KLK1 | |
| SCHEMBL14485834 | 0.91 | KLKB1 (0.86) | KLKB1KLK1 | |
| SCHEMBL17268027 | 0.90 | KLKB1 (0.81) | KLKB1KLK1 | |
| SCHEMBL23517198 | 0.89 | KLKB1 (0.91) | KLKB1KLK1 | |
| SCHEMBL21699873 | 0.89 | KLKB1 (0.91) | KLKB1KLK1 | |
| SCHEMBL17268102 | 0.89 | KLKB1 (0.91) | KLKB1KLK1 | |
| SCHEMBL14555079 | 0.89 | KLKB1 (0.91) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729443-B3 | BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2020-02-12 | — | — | EP | disclosed |