SCHEMBL21670528

SCHEMBL21670528

CCCOc1ccc(Nc2ccc(-c3cc(-c4ccc(OCC)cc4OCC)nc(-c4ccc(OCC)cc4OCC)c3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
KDM4E B2RXH2 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
ALOX5 P09917 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 2/20 0.38
MAPK13 O15264 1/20 0.38
GCGR P47871 1/20 0.38
MAPK12 P53778 1/20 0.38
MAPK11 Q15759 1/20 0.38
MAPK14 Q16539 1/20 0.38
SYK P43405 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
RAD52 P43351 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525961 1.00 MAPT (0.44) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL21670524 0.95 KDM4E (0.43) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL30525976 0.95 KDM4E (0.43) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL21670518 0.94 KDM4E (0.46) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL30525957 0.94 KDM4E (0.46) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL21670577 0.93 KDM4E (0.41) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL30526003 0.93 KDM4E (0.41) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL21670534 0.92 PTPN11 (0.41) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL30525994 0.92 PTPN11 (0.41) MAPTKDM4ESMN1; SMN2LMNATP53
SCHEMBL29048661 0.89 MAPT (0.40) MAPTKDM4ESMN1; SMN2LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed