SCHEMBL21670544

SCHEMBL21670544

CCOc1ccc(N(c2ccc(OCC)cc2)c2ccc(-c3cc(-c4ccc(OCC)cc4OCC)nc(-c4ccc(OCC)cc4OCC)c3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MCL1 Q07820 1/20 0.39
MAPT P10636 2/20 0.38
NPC1 O15118 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NQO1 P15559 1/20 0.37
PARP1 P09874 1/20 0.37
CYP11B1 P15538 2/20 0.36
CYP11B2 P19099 2/20 0.36
CYP19A1 P11511 1/20 0.36
ERN1 O75460 1/20 0.36
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
CDC25C P30307 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21670517 1.00 KDM4E (0.47) KDM4ELMNASMN1; SMN2TP53GAA
SCHEMBL30526002 1.00 KDM4E (0.47) KDM4ELMNASMN1; SMN2TP53GAA
SCHEMBL30525965 1.00 KDM4E (0.47) KDM4ELMNASMN1; SMN2TP53GAA
SCHEMBL30525986 0.94 KDM4E (0.43) KDM4ELMNASMN1; SMN2TP53ALDH1A1
SCHEMBL30525973 0.94 SMN1; SMN2 (0.43) KDM4ELMNASMN1; SMN2TP53GAA
SCHEMBL21670562 0.94 SMN1; SMN2 (0.43) KDM4ELMNASMN1; SMN2TP53GAA
SCHEMBL21670551 0.94 SMN1; SMN2 (0.43) KDM4ELMNASMN1; SMN2TP53GAA
SCHEMBL21670515 0.94 KDM4E (0.43) KDM4ELMNASMN1; SMN2TP53ALDH1A1
SCHEMBL21670527 0.94 KDM4E (0.43) KDM4ELMNASMN1; SMN2TP53ALDH1A1
SCHEMBL30525962 0.94 SMN1; SMN2 (0.43) KDM4ELMNASMN1; SMN2TP53GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed