SCHEMBL21670671

SCHEMBL21670671

[SiH3]C#CI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263134 0.63
SCHEMBL1285289 0.54
SCHEMBL155684 0.50
SCHEMBL12476914 0.50
SCHEMBL2397881 0.50
SCHEMBL21670648 0.50
SCHEMBL242411 0.50
SCHEMBL706512 0.50
SCHEMBL7040850 0.50
SCHEMBL3254858 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818523-B Process for preparing 5-en-1-ynes and compounds derived therefrom 信越化学工业株式会社 2023-05-02 CN disclosed
EP-3608302-B1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND SHINETSU CHEMICAL CO (JP) 2021-10-20 EP disclosed
US-10781146-B2 Process for preparing a 5-alken-1-yne compound, (6Z)-1,1-dialkoxy-6-nonen-2-yne compound, (2E,6Z)-2,6-nonadienal and (2E)-cis-6,7-epoxy-2-nonenal, and 1,1-dialkoxy-6-nonen-2-yne compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-09-22 US disclosed
CN-110818523-A Process for preparing 5-en-1-ynes and their derivatives and 1, 1-dialkoxy-6-nonene-2-ynes 信越化学工业株式会社 2020-02-21 CN disclosed
US-20200048161-A1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608302-A1 PROCESS FOR PREPARING A 5-ALKEN-1-YNE COMPOUND, (6Z)-1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND, (2E,6Z)-2,6-NONADIENAL AND (2E)-CIS-6,7-EPOXY-2-NONENAL, AND 1,1-DIALKOXY-6-NONEN-2-YNE COMPOUND Shin-Etsu Chemical Co., Ltd. (JP) 2020-02-12 EP disclosed