Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 5/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21278330 | 1.00 | CD274 (0.38) | CD274PDCD1LG2NOS3NOS1NOS2 | |
| SCHEMBL4241883 | 0.88 | — | — | |
| SCHEMBL16750993 | 0.88 | — | — | |
| SCHEMBL17780160 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL22659614 | 0.86 | CD274 (0.39) | CD274PDCD1LG2NOS3NOS1NOS2 | |
| SCHEMBL21673402 | 0.81 | CD274 (0.41) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL21673404 | 0.81 | CD274 (0.41) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL94282 | 0.78 | — | — | |
| SCHEMBL14285557 | 0.78 | — | — | |
| SCHEMBL24004296 | 0.78 | CD274 (0.39) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831823-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020025030-A1 | PREPARATION AND APPLICATION OF AROMATIC COMPOUND HAVING IMMUNOREGULATORY FUNCTION | 上海轶诺药业有限公司 | 2020-02-06 | — | — | WO | disclosed |