Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17236378 | 1.00 | KMT2A (0.36) | KMT2AALDH1A1CA1CA2CA12 | |
| SCHEMBL18763334 | 0.98 | KMT2A (0.33) | KMT2AALDH1A1KDM4E | |
| SCHEMBL25767352 | 0.78 | F2 (0.39) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL20706312 | 0.77 | SMN1; SMN2 (0.45) | KMT2AALDH1A1CA1CA2CA12 | |
| SCHEMBL22014089 | 0.77 | SMN1; SMN2 (0.45) | KMT2AALDH1A1CA1CA2CA12 | |
| SCHEMBL25753732 | 0.75 | F2 (0.35) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL13497357 | 0.74 | F2 (0.41) | KMT2AALDH1A1CA1CA2CA12 | |
| SCHEMBL10145581 | 0.72 | KMT2A (0.39) | KMT2AALDH1A1CA1CA2CA12 | |
| SCHEMBL6778032 | 0.72 | KMT2A (0.39) | KMT2AALDH1A1CA1CA2CA12 | |
| SCHEMBL12132349 | 0.72 | KMT2A (0.39) | KMT2AALDH1A1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |