Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | STS | P08842 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139961 | 0.84 | STS (0.56) | SMN1; SMN2STSTP53ALDH1A1NPC1 | |
| SCHEMBL16846251 | 0.80 | STS (0.61) | SMN1; SMN2STSTP53ALDH1A1NPC1 | |
| SCHEMBL3161476 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2STSTP53ALDH1A1MAPT | |
| SCHEMBL21674297 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2STSTP53POLBGPR119 | |
| SCHEMBL5575926 | 0.78 | STS (0.57) | SMN1; SMN2STSTP53ALDH1A1NPC1 | |
| SCHEMBL6424545 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2STSTP53MAPTPOLB | |
| SCHEMBL22266052 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2STSTP53ALDH1A1MAPT | |
| SCHEMBL5187640 | 0.76 | DPP4 (0.60) | SMN1; SMN2STSTP53MAPTPOLB | |
| SCHEMBL3155717 | 0.75 | MEN1 (0.58) | SMN1; SMN2TP53ALDH1A1NPC1MAPT | |
| SCHEMBL4306307 | 0.75 | MEN1 (0.57) | SMN1; SMN2STSTP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |