Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16721631 | 0.89 | BRD4 (0.78) | BRD4NR3C1HTT | |
| SCHEMBL16722686 | 0.89 | BRD4 (0.78) | BRD4NR3C1HTT | |
| SCHEMBL16721748 | 0.88 | BRD4 (1.00) | BRD4NR3C1 | |
| SCHEMBL16721284 | 0.88 | BRD4 (1.00) | BRD4NR3C1 | |
| SCHEMBL16722434 | 0.88 | BRD4 (0.86) | BRD4NR3C1 | |
| SCHEMBL16721229 | 0.87 | BRD4 (0.84) | BRD4NR3C1HTT | |
| SCHEMBL16722031 | 0.87 | BRD4 (0.75) | BRD4NR3C1HTT | |
| SCHEMBL16722033 | 0.87 | BRD4 (0.75) | BRD4NR3C1HTT | |
| SCHEMBL21674955 | 0.87 | BRD4 (0.88) | BRD4NR3C1HTT | |
| SCHEMBL16722227 | 0.87 | BRD4 (0.88) | BRD4NR3C1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |