Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.60 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | BRD2 | P25440 | 3/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16721513 | 1.00 | BRD4 (0.60) | BRD4AVPR2AVPR1AOXTRBRD2 | |
| SCHEMBL16721973 | 0.92 | BRD4 (0.66) | BRD4NOTUM | |
| SCHEMBL21675133 | 0.87 | BRD4 (0.60) | BRD4AVPR2AVPR1ABRD2BRD3 | |
| SCHEMBL16721785 | 0.87 | BRD4 (0.60) | BRD4AVPR2AVPR1ABRD2BRD3 | |
| SCHEMBL16722450 | 0.86 | BRD4 (0.57) | BRD4AVPR1ANOTUMMMP1MMP9 | |
| SCHEMBL21675260 | 0.84 | BRD4 (0.60) | BRD4NOTUM | |
| SCHEMBL16722347 | 0.84 | BRD4 (0.60) | BRD4NOTUM | |
| SCHEMBL21674581 | 0.82 | BRD4 (0.58) | BRD4NOTUM | |
| SCHEMBL16721860 | 0.82 | BRD4 (0.58) | BRD4NOTUM | |
| SCHEMBL16721838 | 0.81 | BRD4 (0.55) | BRD4BRD2BRD3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |