Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16723328 | 1.00 | BRD4 (0.61) | BRD4MEN1KMT2ALMNAHTT | |
| SCHEMBL16723207 | 0.93 | BRD4 (0.64) | BRD4LMNAHTTSMN1; SMN2BRD2 | |
| SCHEMBL16723336 | 0.90 | BRD4 (0.78) | BRD4BRD2 | |
| SCHEMBL16723346 | 0.89 | BRD4 (0.60) | BRD4LMNAHTTSMN1; SMN2 | |
| SCHEMBL16721243 | 0.89 | BRD4 (0.59) | BRD4BRD2BRD3 | |
| SCHEMBL17018059 | 0.89 | BRD4 (0.76) | BRD4LMNAHTTSMN1; SMN2BRD2 | |
| SCHEMBL16723212 | 0.89 | BRD4 (0.65) | BRD4LMNAHTTSMN1; SMN2BRD2 | |
| SCHEMBL16723239 | 0.88 | BRD4 (0.63) | BRD4LMNAHTTSMN1; SMN2BRD2 | |
| SCHEMBL21532100 | 0.87 | BRD4 (0.60) | BRD4LMNAHTTSMN1; SMN2 | |
| SCHEMBL16723376 | 0.87 | BRD4 (0.56) | BRD4KMT2ABRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |