Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18930526 | 1.00 | CACNA1B (0.41) | CACNA1BGPR119ATMCTSSCTSK | |
| SCHEMBL21169944 | 1.00 | CACNA1B (0.41) | CACNA1BGPR119ATMCTSSCTSK | |
| SCHEMBL21144653 | 0.86 | SLC1A2 (0.39) | CACNA1BACACBHRH3 | |
| SCHEMBL21144867 | 0.86 | SLC1A2 (0.39) | CACNA1BACACBHRH3 | |
| SCHEMBL21144654 | 0.86 | SLC1A2 (0.39) | CACNA1BACACBHRH3 | |
| SCHEMBL21144866 | 0.86 | SLC1A2 (0.39) | CACNA1BACACBHRH3 | |
| SCHEMBL18930771 | 0.85 | ATM (0.43) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL21144689 | 0.82 | ATM (0.40) | GPR119ATMCTSSCTSKCTSL | |
| SCHEMBL21144891 | 0.82 | ATM (0.40) | GPR119ATMCTSSCTSKCTSL | |
| SCHEMBL21144687 | 0.82 | ATM (0.40) | GPR119ATMCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |