⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21516144 | 0.70 | — | — | |
| SCHEMBL16312100 | 0.67 | — | — | |
| SCHEMBL14627702 | 0.67 | — | — | |
| SCHEMBL9071622 | 0.67 | — | — | |
| SCHEMBL21324137 | 0.61 | — | — | |
| SCHEMBL17623045 | 0.61 | — | — | |
| SCHEMBL14433985 | 0.61 | — | — | |
| SCHEMBL5035393 | 0.61 | — | — | |
| SCHEMBL15830439 | 0.61 | — | — | |
| SCHEMBL17383885 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023710-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTA[C]PYRROLES, SUBSTITUTED DIHYDROPYRROLIZINES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-01-30 | — | — | WO | disclosed |