Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21676831 | 0.93 | MAPK10 (0.47) | MAPK10NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21642754 | 0.87 | MAPK10 (0.61) | MAPK10 | |
| SCHEMBL21642881 | 0.83 | MAPK10 (0.48) | MAPK10NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21642756 | 0.83 | MAPK10 (0.45) | MAPK10NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21642813 | 0.79 | MAPK10 (0.61) | MAPK10 | |
| SCHEMBL21642785 | 0.78 | MAPK10 (0.47) | MAPK10NPC1RAB9APDE10A | |
| SCHEMBL20633937 | 0.77 | MAPK10 (0.79) | MAPK10 | |
| SCHEMBL20633865 | 0.76 | MAPK10 (0.47) | MAPK10NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21642801 | 0.75 | MAPK10 (0.48) | MAPK10PDE10ACYP1A2 | |
| SCHEMBL21676897 | 0.75 | MAPK10 (0.48) | MAPK10NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781201-B2 | Benzimidazole derivative having JNK inhibitory activity and use thereof | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2020-09-22 | — | — | US | disclosed |
| US-20200039959-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY AND USE THEREOF | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039959-A1 | NOVEL BENZIMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY AND USE THEREOF | MAPKAPK3, MAPK3, MAP3K3 | MAPK10 50/4885NPC1 1422/4885RAB9A 2443/4885 |
| US-10781201-B2 | Benzimidazole derivative having JNK inhibitory activity and use thereof | MAPKAPK3, MAPK3, MAP3K3 | MAPK10 50/4885NPC1 1373/4885RAB9A 2734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.