Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171277 | 0.94 | KMT2A (0.42) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2168701 | 0.92 | KMT2A (0.43) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2180812 | 0.91 | NPC1 (0.43) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2169356 | 0.91 | MAOB (0.48) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2169397 | 0.90 | KMT2A (0.42) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2168993 | 0.90 | NPC1 (0.46) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2168862 | 0.90 | KMT2A (0.41) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2171181 | 0.89 | NPC1 (0.44) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2179221 | 0.89 | NPC1 (0.45) | KMT2ANPC1RAB9AMAOBTP53 | |
| SCHEMBL2168075 | 0.89 | NPC1 (0.45) | KMT2ANPC1RAB9AMAOBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |