Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GUSB | P08236 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011938 | 0.81 | MAPT (0.63) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL13780775 | 0.81 | MAPT (0.63) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL6714683 | 0.80 | MAPT (0.67) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL6714688 | 0.80 | MAPT (0.67) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL30779687 | 0.79 | ABCG2 (0.66) | MAPTMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL21644528 | 0.79 | ABCG2 (0.66) | MAPTMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL30000672 | 0.79 | MAPT (0.65) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL31412225 | 0.77 | MAPT (0.61) | MAPTKDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL5450213 | 0.76 | GUSB (0.74) | MAPTGUSBCYP2C19BCHEMAOB | |
| SCHEMBL5450210 | 0.76 | GUSB (0.74) | MAPTGUSBCYP2C19BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | MAPT 1750/4885KDM4E 3893/4885MEN1 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.