Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682881 | 1.00 | POLQ (0.56) | POLQMAPK1OPRK1GCKPDPK1 | |
| SCHEMBL21706022 | 0.89 | POLQ (0.57) | POLQMAPK1CDK5CDK5R1CCNA2 | |
| SCHEMBL21682902 | 0.89 | POLQ (0.53) | POLQMAPK1CDK5CDK5R1CCNA2 | |
| SCHEMBL21682903 | 0.89 | POLQ (0.53) | POLQMAPK1CDK5CDK5R1CCNA2 | |
| SCHEMBL21706143 | 0.88 | POLQ (0.55) | POLQCDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL21705908 | 0.87 | POLQ (0.42) | POLQMAPK1GCKCDK5CDK5R1 | |
| SCHEMBL21705907 | 0.87 | POLQ (0.42) | POLQMAPK1GCKCDK5CDK5R1 | |
| SCHEMBL21682887 | 0.86 | POLQ (0.43) | POLQGCKCDK5CDK5R1CCNA2 | |
| SCHEMBL21706123 | 0.86 | POLQ (0.41) | POLQMAPK1GCKCDK5CDK5R1 | |
| SCHEMBL21706025 | 0.86 | POLQ (0.41) | POLQGCKCDK5CDK5R1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030924-A1 | THIAZOLEUREAS AS ANTICANCER AGENTS | ARTIOS PHARMA LIMITED (GB) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030924-A1 | THIAZOLEUREAS AS ANTICANCER AGENTS | ARTIOS PHARMA LIMITED (GB) | 2020-02-13 | — | — | WO | disclosed |