Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25952083 | 0.90 | MAP4K1 (0.48) | MAP4K1 | |
| SCHEMBL21683967 | 0.87 | MAP4K1 (0.54) | MAP4K1 | |
| SCHEMBL21684816 | 0.86 | MAP4K1 (0.59) | MAP4K1 | |
| SCHEMBL21684820 | 0.86 | MAP4K1 (0.59) | MAP4K1 | |
| SCHEMBL21684811 | 0.86 | MAP4K1 (0.59) | MAP4K1 | |
| SCHEMBL21684893 | 0.86 | MAP4K1 (0.68) | MAP4K1 | |
| SCHEMBL21684895 | 0.86 | MAP4K1 (0.68) | MAP4K1 | |
| SCHEMBL31450449 | 0.86 | MAP4K1 (0.52) | MAP4K1 | |
| SCHEMBL21684891 | 0.86 | MAP4K1 (0.68) | MAP4K1 | |
| SCHEMBL30467331 | 0.86 | MAP4K1 (0.68) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3833348-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC (US) | 2021-06-16 | — | — | EP | disclosed |
| WO-2020033784-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC. (US) | 2020-02-13 | — | — | WO | disclosed |