SCHEMBL21686464

SCHEMBL21686464

Oc1ccc2ccc(O)c(/N=N/c3ccc(N(Cc4ccccn4)Cc4ccccn4)cc3)c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
KMT2A Q03164 7/20 0.49
MEN1 O00255 6/20 0.49
TDP1 Q9NUW8 5/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
HSP90AA1 P07900 3/20 0.49
LMNA P02545 3/20 0.49
GAA P10253 3/20 0.49
ALPL P05186 1/20 0.49
ALPI P09923 1/20 0.49
ALPG P10696 1/20 0.49
CASP3 P42574 1/20 0.49
RECQL P46063 1/20 0.49
MMP14 P50281 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
POLB P06746 3/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21686488 0.90 MAPT (0.56) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24358534 0.85 MAPT (0.42) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24358533 0.83 MAPT (0.48) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24358379 0.83 MAPT (0.44) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24288345 0.83 MAPT (0.44) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL21686491 0.81 EGFR (0.51) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL21686466 0.81 MAPT (0.35) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24288346 0.79 MAPT (0.41) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24282732 0.79 MAPT (0.41) MAPTKMT2AMEN1TDP1L3MBTL1
SCHEMBL24279176 0.79 MAPT (0.47) MAPTKMT2AMEN1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3362518-B1 SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS THE UWM RES FOUNDATION INC (US) 2022-04-27 EP disclosed
US-11275071-B2 Sensor dyes for real-time sensing of metal ions in aqueous environments UWM RESEARCH FOUNDATION, INC. (US) 2022-03-15 US disclosed
US-20200033314-A1 SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS ADVANCED CHEMICAL SYSTEMS, INC. 2020-01-30 US disclosed