Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ME2 | P23368 | 1/20 | 0.37 |
| ▸ | ME1 | P48163 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21686620 | 0.90 | PHLPP2 (0.49) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL21686447 | 0.88 | PHLPP2 (0.50) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL21686650 | 0.88 | PHLPP2 (0.52) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL24358410 | 0.87 | PHLPP2 (0.58) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL21686624 | 0.84 | KMT2A (0.51) | PHLPP2CYP1A2HIF1AHPGDKMT2A | |
| SCHEMBL21686651 | 0.84 | PHLPP2 (0.47) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL21686652 | 0.81 | PHLPP2 (0.44) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL21686429 | 0.78 | PHLPP2 (0.61) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL21686622 | 0.78 | KMT2A (0.53) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 | |
| SCHEMBL24358535 | 0.77 | PHLPP2 (0.43) | PHLPP2CYP1A2HIF1ACYP3A4STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362518-B1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | THE UWM RES FOUNDATION INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-11275071-B2 | Sensor dyes for real-time sensing of metal ions in aqueous environments | UWM RESEARCH FOUNDATION, INC. (US) | 2022-03-15 | — | — | US | disclosed |
| US-20200033314-A1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | ADVANCED CHEMICAL SYSTEMS, INC. | 2020-01-30 | — | — | US | disclosed |