SCHEMBL2168964

SCHEMBL2168964

c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4cnc5ccccc5n4)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.58
RAB9A P51151 8/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
BCHE P06276 1/20 0.58
MAPT P10636 5/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.52
HPGD P15428 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TLR9 Q9NR96 1/20 0.50
PDGFRB P09619 1/20 0.49
KDR P35968 1/20 0.49
FLT3 P36888 1/20 0.49
KMT2A Q03164 2/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
GLA P06280 1/20 0.45
GAA P10253 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12146687 0.98 NPC1 (0.60) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL12146699 0.98 NPC1 (0.60) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL12146690 0.98 NPC1 (0.60) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL12146722 0.97 NPC1 (0.62) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL2481674 0.97 NPC1 (0.62) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL12207317 0.97 NPC1 (0.62) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL23204881 0.93 NPC1 (0.66) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL12146703 0.91 NPC1 (0.56) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL12146691 0.89 NPC1 (0.54) NPC1RAB9ASMN1; SMN2BCHEMAPT
SCHEMBL24596471 0.88 NPC1 (0.72) NPC1RAB9ASMN1; SMN2BCHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410688-B2 Light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-02 US disclosed
US-7985974-B2 Light-emitting element, light-emitting device, lighting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-07-26 US disclosed
US-20100133573-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-03 US disclosed
US-20100109518-A1 Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-05-06 US disclosed