SCHEMBL216905

SCHEMBL216905

COc1ccc2ccc(O)cc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
CASP3 P42574 2/20 0.62
SENP8 Q96LD8 2/20 0.62
SENP7 Q9BQF6 2/20 0.62
SENP6 Q9GZR1 2/20 0.62
CYP1A2 P05177 2/20 0.61
CYP2A6 P11509 1/20 0.61
ABL1 P00519 1/20 0.58
ABCB1 P08183 1/20 0.58
BCR P11274 1/20 0.58
ESR1 P03372 4/20 0.54
RAB9A P51151 1/20 0.52
ESR2 Q92731 3/20 0.50
KDM4E B2RXH2 1/20 0.50
FLT3 P36888 1/20 0.50
LTA4H P09960 1/20 0.50
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10380118 1.00 KMT2A (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL31553173 1.00 KMT2A (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL29869048 0.96 ABL1 (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL547847 0.96 ABL1 (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL31554258 0.96 ABL1 (0.62) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL14885200 0.94 KMT2A (0.57) KMT2AMEN1CASP3SENP8SENP7
Betanaphthol SCHEMBL10802368 0.92 CYP1A2 (0.76) KMT2AMEN1CASP3SENP8SENP7
Formic Acid SCHEMBL28764690 0.91 KMT2A (0.58) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL18966088 0.88 ABL1 (0.55) KMT2AMEN1CASP3SENP8SENP7
SCHEMBL443528 0.86 CYP2A6 (0.80) KMT2AMEN1CASP3SENP7CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117966179-A N- (3- (2-hydroxynaphthalene-1-yl) -4-hydroxyphenyl) -4-toluenesulfonamide compound and preparation method and application thereof 安徽理工大学 2024-05-03 CN claimed
CN-117285678-A Heat-resistant macromolecular rubber anti-aging agent and preparation method thereof 山东龙腾新材料有限公司 2023-12-26 CN claimed
CN-114874153-B Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2023-11-17 CN claimed
CN-112679321-B New green method for preparing 1-diaryl methyl substituted-2-naphthol compound 湖南理工学院 2023-08-08 CN claimed
CN-114874153-A Synthetic method of naphtho [2,1-d ] oxazole compound 湖南第一师范学院 2022-08-09 CN claimed
CN-112999230-B Application of cryptotanshinone in preparation of bacterial respiratory chain inhibitor 浙江中医药大学 2022-08-02 CN claimed
CN-111233932-B Chiral phosphoric acid with spiro indane skeleton and preparation method and application thereof 南方科技大学 2022-01-28 CN claimed
CN-111518086-B Oxoindole-naphthofuran derivatives, preparation method and application thereof, and pharmaceutical composition and preparation containing same 广州医科大学 2021-08-06 CN claimed
CN-112999230-A Application of cryptotanshinone in preparation of bacterial respiratory chain inhibitor 浙江中医药大学 2021-06-22 CN claimed
CN-112679321-A Green novel method for preparing 1-diarylmethyl substituted-2-naphthol compound 湖南理工学院 2021-04-20 CN claimed
US-5899212-A CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE NOVO NORDISK A/S (DK) 1999-05-04 US claimed
WO-1998046820-A1 ENZYMATIC DISCHARGE PRINTING OF DYED TEXTILES NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1998-10-22 WO claimed
EP-0697854-B1 USE OF HYDROXYNAPHTHALENES IN COLOURING AGENTS HENKEL KGAA (DE) 1997-03-05 EP claimed
EP-0707637-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1996-04-24 EP claimed
EP-0697854-A1 USE OF HYDROXYNAPHTHALENES IN COLOURING AGENTS HENKEL KGAA (DE) 1996-02-28 EP claimed
EP-0679183-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK A/S (DK) 1995-11-02 EP claimed
WO-1995001426-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1995-01-12 WO claimed
WO-1994026241-A1 USE OF HYDROXYNAPHTHALENES IN COLOURING AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-11-24 WO claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO claimed
WO-1990006372-A1 SUBSTRATES FOR PEROXIDASE ASSAYING MICROPROBE CORPORATION (US) 1990-06-14 WO claimed