Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229659 | 0.82 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL2227540 | 0.79 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL896466 | 0.76 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL15725457 | 0.76 | HDAC6 (0.85) | HDAC6 | |
| SCHEMBL2224120 | 0.73 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL15725459 | 0.72 | HDAC6 (0.85) | HDAC6 | |
| SCHEMBL2225510 | 0.71 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL2227722 | 0.70 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL2225590 | 0.69 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL15725412 | 0.69 | HDAC6 (0.84) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200030325-A1 | Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof | ACETYLON PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030325-A1 | Reverse Amide Compounds As Protein Deacetylase Inhibitors And Methods Of Use Thereof | HDAC6, HDAC1, HDAC3 | HDAC6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.