SCHEMBL21694686

SCHEMBL21694686

[CH2]CCCCCCCCCC=CC=CCCC

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
ALDH1A1 P00352 1/20 0.45
FASN P49327 1/20 0.44
FAAH O00519 6/20 0.38
TRPV1 Q8NER1 1/20 0.38
KDM4E B2RXH2 1/20 0.37
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9339647 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL19973929 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL19973928 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL18837544 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL25178035 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL18837543 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL25171253 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL29284542 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL21694684 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL26932927 1.00 TSHR (0.45) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
CN-117304048-A Cationic lipid 武田药品工业株式会社 2023-12-29 CN disclosed
CN-112639111-B Method for transfecting cardiomyocytes using cationic lipids 国立大学法人京都大学 2023-07-21 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
US-20220145329-A1 METHOD FOR TRANSFECTION INTO CARDIOMYOCYTES USING CATIONIC LIPID TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-05-12 US disclosed
EP-3842538-A1 METHOD FOR TRANSFECTION INTO CARDIOMYOCYTES USING CATIONIC LIPID Kyoto University (JP) 2021-06-30 EP disclosed
EP-3835287-A1 CATIONIC LIPID Takeda Pharmaceutical Company Limited (JP) 2021-06-16 EP disclosed
CN-112639111-A Method for transfecting cardiomyocytes using cationic lipids 国立大学法人京都大学 2021-04-09 CN disclosed
CN-112533893-A Cationic lipid 武田药品工业株式会社 2021-03-19 CN disclosed
WO-2020032185-A1 METHOD FOR TRANSFECTION INTO CARDIOMYOCYTES USING CATIONIC LIPID 国立大学法人京都大学 2020-02-13 WO disclosed
WO-2020032184-A1 CATIONIC LIPID 武田薬品工業株式会社 2020-02-13 WO disclosed