Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21695323 | 0.88 | MAP3K12 (0.68) | MAP3K12 | |
| SCHEMBL21695271 | 0.88 | MAP3K12 (0.65) | MAP3K12 | |
| SCHEMBL20147795 | 0.88 | MAP3K12 (0.64) | MAP3K12 | |
| SCHEMBL21695270 | 0.86 | MAP3K12 (0.67) | MAP3K12 | |
| SCHEMBL21695301 | 0.86 | MAP3K12 (0.66) | MAP3K12 | |
| SCHEMBL21695284 | 0.85 | MAP3K12 (0.77) | MAP3K12 | |
| SCHEMBL20115345 | 0.84 | MAP3K12 (0.59) | MAP3K12 | |
| SCHEMBL21695266 | 0.81 | MAP3K12 (0.70) | MAP3K12 | |
| SCHEMBL22050896 | 0.81 | MAP3K12 (0.74) | MAP3K12 | |
| SCHEMBL16209931 | 0.80 | MAP3K12 (1.00) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47848-E1 | Biheteroaryl compounds and uses thereof | GENENTECH, INC. (US) | 2020-02-11 | — | — | US | disclosed |