Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14846045 | 0.86 | — | — | |
| SCHEMBL25613968 | 0.83 | — | — | |
| SCHEMBL15214999 | 0.83 | — | — | |
| SCHEMBL5410669 | 0.82 | TAAR1 (0.31) | TAAR1 | |
| SCHEMBL9194525 | 0.79 | — | — | |
| SCHEMBL12446707 | 0.79 | GCGR (0.34) | — | |
| SCHEMBL9494017 | 0.78 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL14406595 | 0.78 | — | — | |
| SCHEMBL11415512 | 0.78 | HDAC1 (0.37) | HDAC1HDAC6 | |
| SCHEMBL19779822 | 0.76 | SELL (0.33) | HDAC1HDAC6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608325-A1 | POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | Gilead Sciences, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |